323 players
| # | Player | Carries | Yards▼ | TD | Yds/Carry | Yds/Game | Long | 1st Downs | Stuffs | 10+ | 20+ | Fumbles | Fum Lost |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | James Cook | 309 | 1,621 | 12 | 5.3 | 95.4 | 64 | 68 | 33 | 39 | 9 | 6 | 3 |
| 2 | Derrick Henry | 307 | 1,595 | 16 | 5.2 | 93.8 | 59 | 79 | 47 | 36 | 17 | 5 | 3 |
| 3 | Jonathan Taylor | 323 | 1,585 | 18 | 4.9 | 93.2 | 83 | 84 | 49 | 36 | 9 | 2 | 1 |
| 4 | Bijan Robinson | 287 | 1,478 | 7 | 5.2 | 86.9 | 93 | 63 | 43 | 36 | 8 | 3 | 2 |
| 5 | De'Von Achane | 238 | 1,350 | 8 | 5.7 | 84.4 | 59 | 56 | 49 | 40 | 13 | 1 | 0 |
| 6 | Kyren Williams | 259 | 1,252 | 10 | 4.8 | 73.6 | 34 | 74 | 32 | 26 | 6 | 2 | 2 |
| 7 | Jahmyr Gibbs | 243 | 1,223 | 13 | 5.0 | 71.9 | 78 | 56 | 46 | 27 | 10 | 2 | 1 |
| 8 | Christian McCaffrey | 311 | 1,202 | 10 | 3.9 | 70.7 | 41 | 71 | 58 | 27 | 3 | 1 | 0 |
| 9 | Javonte Williams | 252 | 1,201 | 11 | 4.8 | 75.1 | 66 | 67 | 29 | 26 | 6 | 1 | 1 |
| 10 | Saquon Barkley | 280 | 1,140 | 7 | 4.1 | 71.3 | 65 | 48 | 68 | 28 | 4 | 0 | 0 |
| 11 | Travis Etienne | 260 | 1,107 | 7 | 4.3 | 65.1 | 71 | 48 | 55 | 26 | 7 | 0 | 0 |
| 12 | D'Andre Swift | 223 | 1,087 | 9 | 4.9 | 67.9 | 25 | 62 | 27 | 30 | 5 | 2 | 2 |
| 13 | Tony Pollard | 242 | 1,082 | 5 | 4.5 | 63.6 | 65 | 48 | 34 | 27 | 6 | 3 | 2 |
| 14 | Rico Dowdle | 236 | 1,076 | 6 | 4.6 | 63.3 | 53 | 51 | 34 | 24 | 5 | 1 | 1 |
| 15 | Breece Hall | 243 | 1,065 | 4 | 4.4 | 66.6 | 59 | 57 | 46 | 26 | 8 | 2 | 2 |
| 16 | Kenneth Walker | 221 | 1,027 | 5 | 4.7 | 60.4 | 55 | 46 | 42 | 33 | 10 | 0 | 0 |
| 17 | Chase Brown | 232 | 1,019 | 6 | 4.4 | 59.9 | 37 | 52 | 27 | 24 | 6 | 1 | 0 |
| 18 | Ashton Jeanty | 266 | 975 | 5 | 3.7 | 57.4 | 64 | 44 | 71 | 24 | 3 | 1 | 1 |
| 19 | Jaylen Warren | 211 | 958 | 6 | 4.5 | 59.9 | 45 | 52 | 31 | 23 | 6 | 1 | 0 |
| 20 | Josh Jacobs | 234 | 929 | 13 | 4.0 | 61.9 | 40 | 55 | 42 | 23 | 3 | 3 | 2 |
| 21 | TreVeyon Henderson | 180 | 911 | 9 | 5.1 | 53.6 | 69 | 45 | 31 | 18 | 6 | 1 | 1 |
| 22 | Quinshon Judkins | 230 | 827 | 7 | 3.6 | 59.1 | 46 | 50 | 51 | 18 | 4 | 0 | 0 |
| 23 | Jacory Croskey-Merritt | 175 | 805 | 8 | 4.6 | 47.4 | 72 | 41 | 32 | 21 | 3 | 3 | 2 |
| 24 | Kyle Monangai | 169 | 783 | 5 | 4.6 | 46.1 | 39 | 40 | 24 | 15 | 3 | 1 | 0 |
| 25 | J.K. Dobbins | 153 | 772 | 4 | 5.0 | 77.2 | 41 | 37 | 22 | 21 | 5 | 0 | 0 |
| 26 | Jordan Mason | 159 | 758 | 6 | 4.8 | 47.4 | 24 | 45 | 28 | 22 | 4 | 2 | 1 |
| 27 | Blake Corum | 145 | 746 | 6 | 5.1 | 43.9 | 48 | 44 | 19 | 23 | 5 | 0 | 0 |
| 28 | Tyrone Tracy | 176 | 740 | 2 | 4.2 | 49.3 | 31 | 39 | 24 | 19 | 3 | 0 | 0 |
| 29 | Zach Charbonnet | 184 | 730 | 12 | 4.0 | 45.6 | 30 | 48 | 41 | 12 | 5 | 0 | 0 |
| 30 | David Montgomery | 158 | 716 | 8 | 4.5 | 42.1 | 72 | 41 | 24 | 15 | 3 | 2 | 1 |
| 31 | Woody Marks | 196 | 703 | 2 | 3.6 | 43.9 | 23 | 39 | 45 | 15 | 2 | 1 | 0 |
| 32 | Kimani Vidal | 155 | 643 | 3 | 4.2 | 53.6 | 59 | 32 | 39 | 13 | 4 | 1 | 0 |
| 33 | Kareem Hunt | 163 | 611 | 8 | 3.8 | 35.9 | 33 | 55 | 22 | 10 | 1 | 2 | 1 |
| 34 | Rhamondre Stevenson | 130 | 603 | 7 | 4.6 | 43.1 | 56 | 29 | 29 | 15 | 7 | 2 | 2 |
| 35 | Bucky Irving | 173 | 588 | 1 | 3.4 | 58.8 | 32 | 27 | 37 | 11 | 1 | 1 | 1 |
| 36 | Josh Allen | 112 | 579 | 14 | 5.2 | 36.2 | 40 | 46 | 27 | 17 | 5 | 6 | 2 |
| 37 | Rachaad White | 132 | 572 | 4 | 4.3 | 33.6 | 39 | 37 | 15 | 13 | 2 | 0 | 0 |
| 38 | Aaron Jones | 132 | 548 | 2 | 4.2 | 45.7 | 31 | 28 | 18 | 12 | 1 | 0 | 0 |
| 39 | Omarion Hampton | 124 | 545 | 4 | 4.4 | 60.6 | 54 | 31 | 30 | 14 | 3 | 0 | 0 |
| 40 | RJ Harvey | 146 | 540 | 7 | 3.7 | 31.8 | 50 | 28 | 31 | 8 | 3 | 1 | 1 |
| 41 | Kenneth Gainwell | 114 | 537 | 5 | 4.7 | 31.6 | 55 | 34 | 24 | 15 | 2 | 1 | 0 |
| 42 | Tyler Allgeier | 143 | 514 | 8 | 3.6 | 30.2 | 21 | 36 | 30 | 14 | 1 | 0 | 0 |
| 43 | Chuba Hubbard | 134 | 511 | 1 | 3.8 | 34.1 | 14 | 31 | 16 | 8 | 0 | 1 | 1 |
| 44 | Nick Chubb | 122 | 506 | 3 | 4.2 | 33.7 | 30 | 20 | 19 | 9 | 3 | 0 | 0 |
| 45 | Chris Rodriguez | 112 | 500 | 6 | 4.5 | 41.7 | 48 | 32 | 15 | 13 | 2 | 0 | 0 |
| 46 | Justin Herbert | 83 | 498 | 2 | 6.0 | 31.1 | 41 | 34 | 15 | 16 | 5 | 4 | 1 |
| 47 | Emanuel Wilson | 125 | 496 | 3 | 4.0 | 31.0 | 15 | 32 | 14 | 12 | 0 | 0 | 0 |
| 48 | Jaxson Dart | 86 | 487 | 9 | 5.7 | 34.8 | 29 | 38 | 14 | 18 | 4 | 3 | 1 |
| 49 | Alvin Kamara | 131 | 471 | 1 | 3.6 | 42.8 | 18 | 21 | 19 | 10 | 0 | 1 | 1 |
| 50 | Isiah Pacheco | 118 | 462 | 1 | 3.9 | 35.5 | 16 | 27 | 11 | 10 | 0 | 0 | 0 |